lifelabs reference ranges

Gullo, D., Latina, A., Frasca, F., Le Moli, R., Pellegriti, G., & Vigneri, R. (2011). This site uses Akismet to reduce spam. Deputy Ontario Medical Director Sorry, your blog cannot share posts by email. Clinical Laboratory, 58(7–8), 725–736. It is anticipated that by November 2018 all LifeLabs laboratory locations will go-live with new Sysmex XN series hematology instrumentation. Oh and BTW I don’t rate the Soldin work either. Symptomatic Relief is Related to Serum Free Triiodothyronine Concentrations during Follow-up in Levothyroxine-Treated Patients with Differentiated Thyroid Cancer. Reference ranges vary by labs. Research in thyroid science continues to rely largely on immunoassay methods in most studies that assess Free T3 and Free T4. ), Endotext (Originally published 2000; Updated February 20, 2017). Are they on a high dose of L-T4 per kg body weight? Reference ranges for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples.Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the area of pathology that is generally concerned with analysis of bodily fluids. Synthroid induces a low T3:T4 ratio that is exaggerated among those with less thyroid gland tissue and higher doses. (2003). In L. J. Therefore we should question whether Abbott’s “recommended” ranges are accurate, because they are motivated to minimize and normalize the lower T3 levels caused by their bestselling drug Synthroid. These outlying low FT3 values found among “healthy” control groups could have been obtained in patients whose FT3 was temporarily lowered by chronic illness or medications, so we doubt whether all the conditions that alter FT3 were excluded. Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients. https://doi.org/10.1530/EJE-16-0193, 8. (4). The new ref ranges of 2.6 – 5.8 pmol/L at LifeLabs are very close to the assay manufacturer’s (Abbott’s) recommended reference ranges shown in Table 3 below, 2.6 – 5.7. Circle = Graves’ disease. The LifeLabs Ontario laboratory now states that it uses Abbott Architect, a laboratory immunoassay kit, according to the Free T3 page on their website. h�b```e``�"�~13 �0P���cÍ8 �,Lb��ݭ_n�;::E+::�J����]�:��b�HФ��F���k�����,p�0�5o`�a�d�\ɜ��>� ���@7E50b ;���0�A� �nv��@� �aL9���| ��@���A�.%���p��@� �(M endstream endobj 366 0 obj <>/Metadata 14 0 R/OCProperties<. https://doi.org/10.1136/bmj.326.7384.311, 10. Graphs reveal that two of the three Free T3 assays that Fillee et al studied — the Architect and the Elecsys — tended to shift even “normal” values upward into the upper 2/3 of the reference range — as shown below, where plots on a Z-test enable fair comparison based on Fillee et al’s 95% reference values. The Free T3 and Free T4 immunoassays reported in methods sections of research reports yield strong enough results for coefficients of variation and their range of accuracy. In a patient with thrombocytopenia, raised IPF levels are an indication of increased peripheral platelet destruction making this parameter particularly useful for supporting a diagnosis of ITP or TTP, and for distinguishing peripheral platelet destruction from bone marrow suppression. Only this can motivate them to get to work on improving the accuracy of testing lower concentrations of Free T3. 42040 | Fax: 416 213 4206  For Inquires, contact LifeLabs Customer Care Centre 1-877-849-3637 Doc # 8229 Ver: 8.0 Current Issued: 25-Jul-2018 Printed copies are uncontrolled Page 3 of 7 Ontario REPORTING OF CRITICAL & ALERT VALUES (CONT’D) ALERT VALUE An alert value is identified as a result that deviates significantly from the reference range and if

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